{"id":8955,"date":"2025-11-20T11:24:40","date_gmt":"2025-11-20T10:24:40","guid":{"rendered":"https:\/\/www.kedrion.it\/?post_type=our_stories&p=8955"},"modified":"2025-11-24T18:14:14","modified_gmt":"2025-11-24T17:14:14","slug":"the-role-of-fviii-beyond-coagulation","status":"publish","type":"our_stories","link":"https:\/\/www.kedrion.it\/en\/our-stories\/the-role-of-fviii-beyond-coagulation\/","title":{"rendered":"The Role of FVIII Beyond Coagulation: From Basic Research to Clinical Implications"},"content":{"rendered":"\n
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Durante il Corso Nazionale della Societ\u00e0 Italiana per lo Studio dell\u2019Emostasi e della Trombosi (SISET), tenutosi a Bergamo dal 23 al 25 ottobre 2025, l\u2019attenzione si \u00e8 focalizzata su un argomento di crescente interesse nella comunit\u00e0 scientifica: le funzioni fisiologiche del fattore VIII endogeno al di l\u00e0 del suo ruolo classico nella coagulazione.<\/span>
\n<\/span>Come ha introdotto il<\/span> Dott. Ezio Zanon<\/b>, il dibattito si \u00e8 concentrato sulle funzioni meno note di questa proteina, guardando oltre la sua<\/span> tradizionale attivit\u00e0 emostatic<\/b>a. Dalle cellule endoteliali al metabolismo osseo, la ricerca di base sta infatti rivelando come il fattore VIII possa avere un\u2019influenza pi\u00f9 ampia e complessa sul<\/span> funzionamento dell\u2019organismo<\/b>.<\/span><\/p>\n

Diversi specialisti hanno offerto prospettive complementari su questi nuovi orizzonti della ricerca. <\/span>La Dott.ssa Cristina Orgasi<\/b> ha illustrato i risultati di uno studio in vitro e su modello murino sul ruolo del <\/span>FVIII <\/b>nel<\/span>
\n<\/span>mantenimento della <\/span>funzionalit\u00e0 endoteliale <\/b>e nel<\/span> mantenimento della barriera endoteliale<\/b>.<\/span>
\n<\/span>La <\/span>Dott.ssa Chiara Borsotti<\/b> ha invece approfondito il <\/span>legame tra fattore VIII e metabolismo osseo<\/b>, evidenziando come questa proteina possa contribuire al corretto equilibrio tra formazione e riassorbimento dell\u2019osso. Infine, il <\/span>Prof. Raimondo De Cristofaro<\/b> ha posto l\u2019accento sulle\u00a0 potenziali implicazioni cliniche, sottolineando la necessit\u00e0 di continuare a indagare gli effetti del fattore VIII endogeno anche al di fuori del sistema coagulativo.<\/span><\/p>\n

Sostenere questa sessione \u00e8 stato per Kedrion motivo di orgoglio: un\u2019occasione per favorire l\u2019incontro tra ricerca e clinica, tra innovazione scientifica e impegno quotidiano nella cura.<\/span><\/p>\n <\/div>\n <\/div>\n <\/div>\n<\/div>\n\n\n","protected":false},"featured_media":8950,"parent":0,"menu_order":1,"template":"our_stories\/stories_video.php","categories_our_stories":[104],"class_list":["post-8955","our_stories","type-our_stories","status-publish","has-post-thumbnail","hentry","categories_our_stories-events"],"acf":[],"yoast_head":"\nThe Role of FVIII Beyond Coagulation: From Basic Research to Clinical Implications - Kedrion Biopharma<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kedrion.it\/en\/our-stories\/the-role-of-fviii-beyond-coagulation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Role of FVIII Beyond Coagulation: From Basic Research to Clinical Implications - 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