{"id":8957,"date":"2025-11-20T11:33:51","date_gmt":"2025-11-20T10:33:51","guid":{"rendered":"https:\/\/www.kedrion.it\/?post_type=our_stories&#038;p=8957"},"modified":"2025-11-20T11:33:52","modified_gmt":"2025-11-20T10:33:52","slug":"sergio-siragusa-integrated-management-of-von-willebrand","status":"publish","type":"our_stories","link":"https:\/\/www.kedrion.it\/en\/our-stories\/sergio-siragusa-integrated-management-of-von-willebrand\/","title":{"rendered":"Integrated management of von Willebrand disease in women: insights from Prof. Sergio Siragusa"},"content":{"rendered":"\n<div class=\"container ourStorySingleBlockBanner\">\n    <div class=\"row\">\n        <div class=\"col-lg-6 col-lg-offset-4\">\n            <div class=\"single-story__intro_banner\">\n                <span>#InnovationinTransfusionMedicine<\/span>\n                <p><b>Von Willebrand disease <\/b><span style=\"font-weight: 400;\">(VWD) is one of the <\/span><b>most common congenital bleeding disorders<\/b><span style=\"font-weight: 400;\">, yet it remains among the least recognized. It is caused by a quantitative or qualitative defect of von Willebrand factor, a key protein involved in the blood coagulation process. This alteration leads to an increased tendency to bleed, which may occur mildly and intermittently, <\/span><b>often delaying diagnosis<\/b><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">As explained by<\/span><b> Prof. Sergio Siragusa,<\/b><span style=\"font-weight: 400;\"> Director of the Hematology Unit at AOU \u201cGiaccone\u201d in Palermo, despite its relatively high prevalence in the general population\u2014estimated at about 1 in 1,000 individuals\u2014VWD remains poorly known, particularly in the gynecological setting. In women, it can manifest during the reproductive years with menorrhagia or menstrual irregularities that are frequently mistaken for physiological conditions.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Early recognition of these symptoms<\/b><span style=\"font-weight: 400;\"> is essential to guide diagnosis and prevent potential complications, especially during critical situations such as childbirth or surgical procedures. According to Prof. Siragusa, effective management of this disorder requires a multidisciplinary and collaborative <\/span><b>approach<\/b><span style=\"font-weight: 400;\"> among specialists.<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">\u201cThe menstrual period may represent one of the first symptoms of the disease. This is why it is important for gynecologists to be familiar with the condition and to recognize it through both personal and family medical history.\u201d<\/span><\/i><\/p>\n<p><b>The integrated management <\/b><span style=\"font-weight: 400;\">of von Willebrand disease thus represents a virtuous model of interdisciplinary cooperation, where the synergy between medical specializations improves diagnosis, reduces risks, and optimizes therapeutic pathways.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Kedrion continues to collaborate with the scientific community to promote the dissemination of knowledge and best clinical practices, fostering a more informed and shared approach to the management of congenital bleeding disorders.<\/span><\/p>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\n","protected":false},"featured_media":8945,"parent":0,"menu_order":2,"template":"our_stories\/stories_video.php","categories_our_stories":[104],"class_list":["post-8957","our_stories","type-our_stories","status-publish","has-post-thumbnail","hentry","categories_our_stories-events"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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